.page.safety_tolerability p.corrected_1{-webkit-padding-end:140px;padding-inline-end:140px}.page.safety_tolerability .main{-webkit-padding-after:0!important;padding-block-end:0!important}section .sub_section .image_vertical_carousel{display:flex;flex-direction:column;gap:14px;-webkit-padding-start:105px;padding-inline-start:105px;border-bottom:1px solid #d5d5d5;padding-block:calc(40px - 1em) 50px}section .sub_section .image_vertical_carousel:last-child{border-bottom:none}section.tab_section .sub_section .sub_title{line-height:1.2}section.tab_section .sub_section .sub_title.week24{max-width:930px}section.tab_section .sub_section.table{padding:45px 0}#tab_section_2 .container.tercio>div:first-child{width:calc(30% - var(--container-tercio-gap-half));gap:8px!important}section.tab_section .chart_container{border-radius:2rem;overflow:hidden}.bg-grey{background:linear-gradient(180deg,#d5d5d54a,hsla(0,0%,44%,0))!important}section.tab_section .chart_container .chart_heading{background-color:#182a54;border-radius:2rem 2rem 0 0;border:2px solid white;border-bottom:none;display:flex;justify-content:center;gap:0}main.page .hero_container .subhero .wrapper{display:flex;flex-direction:row;align-items:center;justify-content:space-between;gap:30px;-webkit-margin-after:30px;margin-block-end:60px;-webkit-margin-before:30px;margin-block-start:30px}p.blue.small.disclaimer.center{text-align:center;height:91px;display:flex;justify-content:center;align-items:center;text-transform:uppercase}section .container.middle{gap:var(--container-gap);gap:70px}section .blocks .container,section .container.middle{display:flex;flex-direction:row;justify-content:center;max-width:100%}section .blocks .container{gap:var(--container-gap);gap:45px}section.tab_section .chart_container .chart_heading p.heading{color:white;padding:1rem 1.5rem;text-align:center}section.tab_section .chart_container table{width:100%;background-color:white;border-radius:0 0 2rem 2rem;overflow:hidden}section.tab_section .chart_container table *{font-size:17px;border-color:white!important}section.tab_section .chart_container table thead{background-color:#B7DBD3}section.tab_section .chart_container.four-row table thead{background-color:#F5F5F5}section.tab_section .chart_container.four-row table tbody tr td:nth-child(2n){background-color:#B7DBD3}section.tab_section .chart_container.four-row .bg_grey_light_cell{background-color:whitesmoke}section.tab_section .chart_container.four-row .bg_grey_cell{background-color:#e2e2e2}section.tab_section .chart_container.four-row .bg_green_cell{background-color:#b7dbd3}section.tab_section .chart_container table thead tr th{line-height:1;font-weight:600;text-align:center;padding:1rem 2rem;color:var(--clr-blue-dark)}section.tab_section .chart_container.four-row table thead tr th{line-height:1;font-weight:400;text-align:center;padding:1rem 2rem;color:var(--clr-blue-dark)}section.tab_section .chart_container table thead tr th sup{font-size:10px}section.tab_section .chart_container table thead tr th span{font-size:16px;font-weight:300}section.tab_section .chart_container table tbody tr{background-color:#E2E2E2}section.tab_section .chart_container table tbody tr:nth-child(2n){background-color:#F5F5F5}section.tab_section .chart_container table tbody tr td{text-align:center;padding:1rem 2rem;width:33%}section.tab_section .chart_container table tbody tr:last-child td:first-child{border-radius:0 0 0 2rem}section.tab_section .chart_container table tbody tr:last-child td:last-child{border-radius:0 0 2rem 0}section .sub_section .image_vertical_carousel .carousel_container{display:flex;gap:22px}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container{display:flex;flex-direction:column;align-items:center;gap:30px}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container .highlight_image{position:relative}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container .highlight_image img.highlight{border-radius:1em;width:690px;object-fit:cover}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container .highlight_image img.lupa{position:absolute;right:17px;top:17px;transition:.2s;border-radius:50px;cursor:pointer}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container .highlight_image img.lupa:hover{outline:1px solid white;transition:.2s}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container p.image_title{text-align:center}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container p.image_description{text-align:center;max-width:450px}section .sub_section .image_vertical_carousel .carousel_container .highlight_image_container p.image_description.corrected_2{max-width:unset}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector{display:flex;flex-direction:column;gap:1em;justify-content:space-between;max-height:450px}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector .miniature_selector_container{display:flex;align-items:center;gap:1em}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector .miniature_selector_container img{border-radius:1em;cursor:pointer;transition:51ms}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector .miniature_selector_container.active img{outline:4px solid var(--clr-teal);transition:51ms}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector .miniature_selector_container .text_container p.day_title{font-weight:700;text-transform:uppercase;font-size:16px;color:var(--clr-blue)}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector .miniature_selector_container.active .text_container p.day_title{color:var(--clr-teal)}section .sub_section .image_vertical_carousel .carousel_container .carousel_selector .miniature_selector_container .text_container p.description{font-size:16px}section.tab_section.lsr{background-color:hsl(0,0%,96%,.75)}section.tab_section.lsr .sub_section{display:flex;flex-direction:column;gap:1em}section.tab_section.lsr .sub_section.table{-webkit-padding-after:80px;padding-block-end:80px}section.tab_section.lsr .image_container,section.tab_section.lsr .image_container a{display:flex;flex-direction:row;gap:20px;align-items:flex-end}section.tab_section.lsr .image_container p{display:flex}section.tab_section.lsr p.table_title{margin-top:1em;text-align:center;-webkit-padding-end:150px;padding-inline-end:150px}section.tab_section .container.charts{gap:45px;margin-top:25px;max-width:100%}section.tab_section .sub_container.chart{gap:16px}section.tab_section .sub_section.blocks .sub_container.box-img{background-color:#B7DBD2;border-radius:0 20px 20px 0;display:flex;flex-direction:column;align-items:flex-start;align-content:flex-start;gap:20px;height:300px;justify-content:center;padding-left:150px;-webkit-padding-end:20PX;padding-inline-end:20PX}section.tab_section .sub_section.blocks .sub_container.box-img-white{background-color:#edf6f4;border-radius:20px 0 0 20px;display:flex;flex-direction:row;align-items:center;align-content:center;gap:40px;height:300px;justify-content:center;padding-left:67px}section.tab_section .sub_section.blocks .sub_container.box-img p,section.tab_section .sub_section.blocks .sub_container.box-img-white p{font-size:17px;font-weight:400;line-height:22px;text-transform:none;width:550px}section.tab_section .sub_section.blocks .sub_container.box-img p.uppercase{text-transform:uppercase}section.tab_section.lsr .sub_container.info img{object-fit:cover;-webkit-margin-start:-5px;margin-inline-start:-5px;-webkit-margin-after:-5px;margin-block-end:-5px}section.tab_section .sub_container.center-img{display:flex;justify-content:center;align-items:center;padding-block:.5rem}section.tab_section.lsr .sub_container.info{display:flex;flex-direction:column;justify-content:space-between!important}section.tab_section.lsr .sub_container.info .corrected_2{-webkit-padding-end:120px;padding-inline-end:120px}section.tab_section.lsr .sub_container.info .corrected_3{-webkit-padding-end:90px;padding-inline-end:90px}section.tab_section.lsr .sub_container.info .corrected_4{-webkit-padding-end:100px;padding-inline-end:100px}section.tab_section.mechanism{-webkit-padding-after:60px;padding-block-end:60px}section.tab_section.mechanism .mechanism_container{margin-top:1em}section.tab_section.mechanism .sub_container .corrected_5{-webkit-padding-end:40px;padding-inline-end:40px}section.tab_section.mechanism .sub_container .corrected_6{-webkit-padding-end:70px;padding-inline-end:70px;text-transform:uppercase}section.tab_section.mechanism .sub_container.over{z-index:20;display:flex;flex-direction:column;gap:38px!important}section.tab_section.mechanism .sub_container.under{z-index:19}section.tab_section.mechanism .sub_container img.mechanism{-webkit-margin-start:-125px;margin-inline-start:-125px}section.tab_section .sub_section.adverse{-webkit-padding-after:80px;padding-block-end:80px}section.tab_section.adverse .adverse_container{-webkit-margin-before:1em;margin-block-start:1em}section.tab_section.adverse .corrected_7{max-width:600px}section.tab_section.adverse .corrected_9{-webkit-padding-end:48px;padding-inline-end:48px}section.tab_section.adverse .corrected_10{-webkit-padding-end:20px;padding-inline-end:20px}section.tab_section .sub_section.blue_banner .corrected_11{max-width:530px;-webkit-margin-start:280px;margin-inline-start:280px}section.tab_section .sub_section.blue_banner{height:159px}section.tab_section .sub_section.blue_banner .wrapper{position:relative;align-items:center;height:100%}section.tab_section .sub_section.blue_banner .wrapper img{position:absolute;left:0;bottom:0;-webkit-margin-start:-70px;margin-inline-start:-70px;-webkit-margin-after:-80px;margin-block-end:-80px;object-fit:cover}section.tab_section.phototoxicity .sub_section.photoallergic{-webkit-padding-after:80px;padding-block-end:80px;background-image:url(/assets/images/safety-tolerability/phototoxicity-woman.png);background-size:cover;background-position:70%;background-repeat:no-repeat}@media (min-width:1441px){section.tab_section.phototoxicity .sub_section.photoallergic{background-position:calc(50% - 20px) 20%;background-size:1440px auto;background-size:contain}}section.tab_section.phototoxicity .sub_section.photoallergic .image_block{display:flex;flex-direction:column;gap:60px;width:870px}section.tab_section.phototoxicity .sub_section.photoallergic .image_block .info_cards{margin-top:calc(30px - 1em);display:flex;gap:30px}section.tab_section.phototoxicity .sub_section.photoallergic .image_block .info_cards .card{box-shadow:-1px 4px 19px -7px rgba(0,0,0,.8);padding:24px;width:269px;height:207px;display:flex;flex-direction:column;gap:1em;align-items:flex-start;background-color:white}section.tab_section.phototoxicity .sub_section.photoallergic .image_block .info_cards .card p.blue{text-transform:uppercase}section.tab_section.phototoxicity .sub_section.photoallergic .image_block .description{width:100%;display:flex;flex-direction:column;align-items:center;gap:22px}section.tab_section.phototoxicity .sub_section.photoallergic .image_block .description p{text-transform:uppercase;font-size:24px;line-height:30px}section.tab_section.phototoxicity .sub_section .corrected_12{max-width:645px;line-height:normal}section.tab_section.phototoxicity .sub_section.info.corrected_13{padding-block:40px}section.tab_section.phototoxicity .sub_section .corrected_14{max-width:600px}section.tab_section.phototoxicity .sub_section.info .sub_container.has_float_image img{bottom:-40px}.sub_section.graphic{-webkit-padding-after:2rem;padding-block-end:2rem}section.tab_section .sub_section.graphic .wrapper{gap:2rem}.tab_block_graphic{display:flex}.tab_block_graphic .tab_column{display:flex;flex-direction:column;gap:8px;width:246px;margin-top:2rem}.tab_block_graphic .tab_column .tab{background-color:#ECECEC;padding:1rem;border-radius:1rem 0 0 1rem;cursor:pointer}.tab_block_graphic .tab_column .tab p{color:#182a54}.tab_block_graphic .tab_column .tab.active{background-color:#182a54}.tab_block_graphic .tab_column .tab.active p{font-weight:700;color:white}.tab_block_graphic .tab_image{display:none;gap:1rem;padding-block:2rem;box-shadow:-2px 1px 10px 9px rgba(0,0,0,.19);border-radius:1rem 0 0 1rem;position:relative;align-items:flex-end;justify-content:flex-start;gap:50px;-webkit-padding-end:70px;padding-inline-end:70px}.tab_block_graphic .tab_image .clearer{position:absolute;height:calc(100% + 40px);width:133px;right:-27px;top:-20px;background:rgb(255,255,255);background:linear-gradient(90deg,rgba(255,255,255,0) 18%,rgba(255,255,255,1) 73%)}.tab_block_graphic .tab_image .references_container{-webkit-margin-after:44px;margin-block-end:44px}.tab_block_graphic .tab_image p.image_reference{font-size:11px;line-height:1.3;width:220px;color:#182a54;-webkit-margin-start:.4rem;margin-inline-start:.4rem;position:relative}.tab_block_graphic .tab_image p.image_reference sup{font-size:7px}.tab_block_graphic .tab_image p.image_reference sup.spec{font-size:9px}.tab_block_graphic .tab_image p.image_reference sup.initial_ref{position:absolute;top:6px;left:-4px}.tab_block_graphic .tab_image.active{display:flex;align-items:center}.tab_block_graphic .tab_image .image_container{display:flex;flex-direction:column;gap:16px;-webkit-padding-start:60px;padding-inline-start:60px}.tab_block_graphic .tab_image .image_container img{object-fit:cover}.tab_block_graphic .tab_image .image_container p{max-width:560px}.corrected_block{max-width:487px}.corrected_proark_1{max-width:260px}.corrected_proark_2{margin-bottom:.5rem}.corrected_proark_3{width:100%;height:auto}.mar-top-image{margin-top:60px}@media (max-width:1240px){.tab_block_graphic .tab_image.active{flex-direction:column;gap:0;align-items:center;justify-content:center}.tab_block_graphic .tab_image .image_container img{object-fit:contain;height:auto}.tab_block_graphic .tab_image .references_container{margin:0;width:100%;-webkit-padding-start:60px;padding-inline-start:60px}.tab_block_graphic .tab_image .references_container p{width:-moz-fit-content;width:fit-content}}@media (max-width:987px){.corrected_proark_1{max-width:unset}div.mobile_weeks,div.mobile_weeks .weeks_container{width:100%;display:flex;flex-direction:column;align-items:center;justify-content:center}div.mobile_weeks .weeks_container{min-height:200px}div.mobile_weeks .weeks_container.top_container{background:rgb(217,217,217);background:linear-gradient(0deg,#d2dce0 150px,rgba(255,255,255,.727328431372549))}div.mobile_weeks .weeks_container.top_container .container_wrapper{-webkit-padding-before:6rem;padding-block-start:6rem}div.mobile_weeks .weeks_container.top_container .triangle_bg{background-color:rgba(226,235,237,1);position:relative;width:100%;height:-moz-fit-content;height:fit-content;max-height:calc(100px - 4px);overflow:hidden;display:flex;align-items:center;justify-content:center}div.mobile_weeks .weeks_container.top_container .triangle_bg .triangle_effect{width:0;height:0;border-color:#d2dce0 transparent transparent;border-style:solid;border-width:100px 200px 0;transform:rotate(0deg)}div.mobile_weeks .weeks_container.bottom_container{background:rgb(226,235,237);background:linear-gradient(180deg,rgba(226,235,237,1),rgba(255,255,255,.727328431372549))}div.mobile_weeks .weeks_container .container_wrapper{display:flex;flex-direction:column;align-items:center;justify-content:center;text-align:center;gap:1rem}div.mobile_weeks .weeks_container .container_wrapper p.week{font-size:32px;font-weight:300}div.mobile_weeks .weeks_container .container_wrapper p.percent{font-size:32px}div.mobile_weeks .weeks_container .container_wrapper p.description{line-height:normal;max-width:200px;font-size:15px}section.tab_section .graphic.only_mobile .graphic_tab_mobile{-webkit-margin-end:-30px;margin-inline-end:-30px;-webkit-padding-end:5px;padding-inline-end:5px;overflow:hidden;border-radius:1rem 0 0 1rem}section.tab_section .graphic.only_mobile .graphic_tab_mobile.active{box-shadow:-1px 4px 19px -7px rgba(0,0,0,.8)}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_heading{display:flex;width:100%;justify-content:space-between;align-items:center;background-color:#ECECEC;padding:1rem;padding-block:16px;transition:.2s}section.tab_section .graphic.only_mobile .graphic_tab_mobile.active .tab_heading{transition:.2s;background-color:var(--clr-blue)}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_heading .toggler{height:46px;width:46px;background-image:url(/assets/svg/tab_mobile_toggler_open.svg);background-size:contain;background-repeat:no-repeat;background-position:50%}section.tab_section .graphic.only_mobile .graphic_tab_mobile.active .tab_heading .toggler{background-image:url(/assets/svg/tab_mobile_toggler_close.svg)}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_heading p.heading{text-transform:uppercase;color:var(--clr-blue);font-size:18px}section.tab_section .graphic.only_mobile .graphic_tab_mobile.active .tab_heading p.heading{color:white;font-weight:600}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_heading img.toggler{width:46px;height:46px}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body{padding:0;display:flex;flex-direction:column;gap:1rem;height:0;overflow:hidden}section.tab_section .graphic.only_mobile .graphic_tab_mobile.active .tab_body{padding:1rem;height:-moz-fit-content;height:fit-content}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .image_container{display:flex;flex-direction:column;gap:1rem}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .image_container p{color:#333333}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .image_container img{width:100%;max-width:calc(100% - 50px);height:auto}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .references_container p{color:var(--clr-blue);font-size:11px;line-height:1.4}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .references_container p sup{font-size:8px}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .references_container{-webkit-padding-start:8px;padding-inline-start:8px}p:has(.initial_ref),section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .references_container p:has(.initial_ref){position:relative;line-height:normal}p:has(.initial_ref) .initial_ref,section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .references_container p:has(.initial_ref) .initial_ref{position:absolute;left:-6px;top:5px}}@media (max-width:787px){section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_body .image_container p{font-size:14px;line-height:normal}section.tab_section .graphic.only_mobile .graphic_tab_mobile .tab_heading p.heading{max-width:260px}.blue b,h1 sup{font-size:17px}p.thin.blue.nocaps{padding-top:25px;padding-bottom:25px}}@media (max-height:761px){h1{font-size:17px}h1 sup{font-size:15px}}@media (min-width:800px) and (max-width:1239px){.container.middle.proak-section-two,.container.proak-section-two{flex-wrap:nowrap!important}.sub_section.proak-margin{margin:75px}section.tab_section .sub_section.blocks .sub_container.box-img{padding-left:20px!important}section .blocks .container{gap:1px}.text_block.gap_half.corrected_block{width:100%!important}.sub_container.chart{width:calc(70% - var(--container-gap-half))!important;display:flex;justify-content:center}}